(i) Red blood cells are destroyed. Anemia occurs. In this condition, hemolytic anemia occurs.
(ii) Spleen and liver of the patient become swollen and enlarged day by day. Lysolecithin is secreted from the spleen.
(iii) Parasites produce antibodies called Haemolysin which destroy red blood cells.
(iv) Digestion of the patient is disturbed.
(v) Patient may die due to brain damage.