The liver appears bifurcated externally as it is covered by a falciform membrane. The liver is divided into four distinct lobes. Right lobe, left lobe, caudate and quadrate lobe. The right segment is the largest, the left segment is the smallest. The right lobe is six times larger than the left lobe. The caudate and quadrate segments are square-like. The liver is covered by a membrane called Gison’s capsule. This membrane divides the liver into lobules or segments. Liver cells are arranged in each lobule like the spokes of a wheel. The space between adjacent lobules is called sinusoid. Between each lobule is a central vein. The right and left hepatic ducts together form the common hepatic/hepatic duct. The common hepatic duct joins with the common bile duct to form the common bile duct. The common bile duct enters the duodenum through the ampulla of Vater.