The process by which nuclear material (DNA) is transferred from one cell to another cell by forming a conjugation channel between two cells is called conjugation. Two bacterial cells of opposite sex (+,Ñ) come close to each other and lie closely side by side. One of them is called Donor and the other Recipient. The walls of two facing cells swell to form the synovial duct. The two ducts grow and touch each other. Later the wall of the contact area melts to form a conjugation canal. Nuclear material (DNA) from the donor cell enters the recipient cell through the pilus. Before the entire nuclear material enters the recipient cell from the donor cell, the two cells separate from each other. As a result, part of the nuclear material enters the recipient cell from the donor cell. The donor cell is destroyed by loss of nuclear material. Later the nuclear material of the donor and recipient fuse to form a zygote. It is called merozygote. Later the merozygote continues to increase in number in the process of bifurcation. Each new cell produced contains donor and acceptor properties. In 1946 scientists Lenderberg and Tatum discovered the conjugation process in bacteria.