The U-shaped tube extending from the proximal convoluted tubule to the distal convoluted tubule is called loop of Henle. This is called nephron leakage. It is located in the medulla and cortex. Its length is 11 mm and diameter is 20 μm. It consists of two parts. Descending limb and Ascending limb. The descending arm extends from the end of the proximal tubule to the medulla and the ascending arm is located in the cortex region. It is called loop of Henle after German medical scientist Friedrich Henle.